Оценена распространенность и сочетание генов сериновых карбапенемаз среди фенотипически множественно-резистентных штаммов K. pneumoniae, выделенных у пациентов отделений хирургии и реанимации различных регионов Республики Беларусь. Методом ПЦР было проведено определение наличия генов сериновых карбапенемаз (KPC, OXA-48, OXA-23, OXA-24) у 115 штаммов фенотипически множественно-резистентных К. pneumoniae. Среди изолятов K. pneumoniae чаще всего выявлялся ген blaОХА-48 – 70 %, гены карбапенемаз blaKРС и blaOXA-24 были детектированы с практически равной частотой 43,6 и 39,1 %. Показано, что у 23,5 % штаммов К. pneumoniae выявлены гены сериновых бета-лактамаз в качестве единственной детерминанты резистентности, а в остальных случаях клебсиеллы являлись носителями генов нескольких типов бета-лактамаз.
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