Циркулирующие опухолевые клетки и циркулирующие раковые стволовые клетки и их детекция методом проточной цитофлуориметрии
В обзоре приведено описание циркулирующих раковых стволовых клеток (цРСК) и циркулирующих опухолевых клеток (ЦОК) в крови человека и методов их определения. цРСК являются одними из главных инициаторов рецидива онкологических заболеваний, что делает их основной мишенью для разработки новых методов лечения. ЦОК являются относительно новыми биомаркерами для ранней диагностики метастазирования, мониторинг содержания которых дает ценную информацию на всех этапах ведения онкопациентов, включая раннюю диагностику заболевания, оценку риска рецидива болезни, определение эффективности химиотерапии с возможностью последующей ее коррекции.
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